ternarynet

DOI: 10.18129/B9.bioc.ternarynet  

Ternary Network Estimation

Bioconductor version: Release (3.16)

Gene-regulatory network (GRN) modeling seeks to infer dependencies between genes and thereby provide insight into the regulatory relationships that exist within a cell. This package provides a computational Bayesian approach to GRN estimation from perturbation experiments using a ternary network model, in which gene expression is discretized into one of 3 states: up, unchanged, or down). The ternarynet package includes a parallel implementation of the replica exchange Monte Carlo algorithm for fitting network models, using MPI.

Author: Matthew N. McCall <mccallm at gmail.com>, Anthony Almudevar <Anthony_Alumudevar at urmc.rochester.edu>, David Burton <David_Burton at urmc.rochester.edu>, Harry Stern <harry.stern at rochester.edu>

Maintainer: McCall N. Matthew <mccallm at gmail.com>

Installation

To install this package, start R (version "4.2") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("ternarynet")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("ternarynet")

 

PDF	R Script	ternarynet: A Computational Bayesian Approach to Ternary Network Estimation
PDF		Reference Manual
Text		NEWS

Details

biocViews	Bayesian, CellBiology, GraphAndNetwork, Network, Software
Version	1.42.0
In Bioconductor since	BioC 2.10 (R-2.15) (11 years)
License	GPL (>= 2)
Depends	R (>= 4.0)
Imports	utils, igraph, methods, graphics, stats, BiocParallel
LinkingTo
Suggests	testthat
SystemRequirements
Enhances	Rmpi, snow
URL
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package	ternarynet_1.42.0.tar.gz
Windows Binary	ternarynet_1.42.0.zip
macOS Binary (x86_64)	ternarynet_1.42.0.tgz
macOS Binary (arm64)	ternarynet_1.42.0.tgz
Source Repository	git clone https://git.bioconductor.org/packages/ternarynet
Source Repository (Developer Access)	git clone git@git.bioconductor.org:packages/ternarynet
Bioc Package Browser	https://code.bioconductor.org/browse/ternarynet/
Package Short Url	https://bioconductor.org/packages/ternarynet/
Package Downloads Report	Download Stats