anota

DOI: 10.18129/B9.bioc.anota  

ANalysis Of Translational Activity (ANOTA).

Bioconductor version: Release (3.16)

Genome wide studies of translational control is emerging as a tool to study verious biological conditions. The output from such analysis is both the mRNA level (e.g. cytosolic mRNA level) and the levl of mRNA actively involved in translation (the actively translating mRNA level) for each mRNA. The standard analysis of such data strives towards identifying differential translational between two or more sample classes - i.e. differences in actively translated mRNA levels that are independent of underlying differences in cytosolic mRNA levels. This package allows for such analysis using partial variances and the random variance model. As 10s of thousands of mRNAs are analyzed in parallell the library performs a number of tests to assure that the data set is suitable for such analysis.

Author: Ola Larsson <ola.larsson at ki.se>, Nahum Sonenberg <nahum.sonenberg at mcgill.ca>, Robert Nadon <robert.nadon at mcgill.ca>

Maintainer: Ola Larsson <ola.larsson at ki.se>

Installation

To install this package, start R (version "4.2") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("anota")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("anota")

 

PDF	R Script	ANalysis Of Translational Activity (anota)
PDF		Reference Manual
Text		NEWS

Details

biocViews	DifferentialExpression, GeneExpression, Microarray, Sequencing, Software
Version	1.46.0
In Bioconductor since	BioC 2.8 (R-2.13) (12 years)
License	GPL-3
Depends	qvalue
Imports	multtest, qvalue
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Depends On Me	tRanslatome
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Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package	anota_1.46.0.tar.gz
Windows Binary	anota_1.46.0.zip
macOS Binary (x86_64)	anota_1.46.0.tgz
macOS Binary (arm64)	anota_1.46.0.tgz
Source Repository	git clone https://git.bioconductor.org/packages/anota
Source Repository (Developer Access)	git clone git@git.bioconductor.org:packages/anota
Bioc Package Browser	https://code.bioconductor.org/browse/anota/
Package Short Url	https://bioconductor.org/packages/anota/
Package Downloads Report	Download Stats